Lasix is a diuretic that is used to treat edema and high blood pressure

Diuretic Pills	Dose	Pice	Globe Delivery 100 %
Lasix Furosemide	40 mg	$0.30
Savings	320 pills	$161

Its active ingredient, furosemide, increases the excretion of sodium, chloride, and water from the body, which leads to a decrease in the volume of fluid in the body.

Main indications

This drug is prescribed in the following cases:

• Edema syndrome in chronic heart failure (if diuretic therapy is necessary);
• Edematous syndrome in chronic renal failure;
• Acute renal failure, including pregnancy and burns (to support fluid excretion);
• Oedema syndrome in nephrotic syndrome (if diuretic therapy is necessary);
• Edematous syndrome in liver disease (if necessary in addition to treatment with aldosterone antagonists);
• Arterial hypertension.

Cautions

During treatment with Lasix, a continuous outflow of urine should be ensured. Patients with partial urinary outflow obstruction require close monitoring, especially in the initial stages of treatment. Treatment with Lasix requires regular medical follow-up. 

Particularly close monitoring is necessary:

• Patients with arterial hypotension; patients who are at special risk due to a significant decrease in BP, such as those with severe stenosis of coronary arteries or major blood vessels supplying the brain; patients with a latent or severe form of diabetes mellitus; patients with gout;
• Patients with hepatorenal syndrome, i.e. with functional renal failure that is associated with severe liver disease; 
• Patients with hypoproteinemia, e.g., associated with nephrotic syndrome (the effect of furosemide may be attenuated simultaneously with potentiation of ototoxicity);
• Cautious dose titration is necessary;
• For premature infants (possible development of nephrocalcinosis/nephrolithiasis); renal function monitoring and renal ultrasonography are required.

        Regular monitoring of sodium, potassium, and serum creatinine levels is recommended during furosemide therapy. Patients at high risk of electrolyte imbalance or with significant additional fluid loss (e.g. due to vomiting, diarrhea, or profuse sweating) require particularly close monitoring.

Hypovolemia or dehydration, as well as any significant electrolyte and acid-base imbalances, should be corrected. This may require temporary discontinuation of furosemide therapy.

Factors such as existing diseases (e.g., cirrhosis of the liver, heart failure), concomitant use of medications, and nutrition affect the development of electrolyte imbalances. For example, potassium deficiency may occur as a result of vomiting or diarrhea.

Dosing regimen

The dosage regimen and method of administration should be adjusted individually, depending on the degree of water-electrolyte imbalance, and the value of glomerular filtration.

Further adjustment of the dosage is necessary, depending on the severity of the patient's condition and the value of diuresis. Usually, the drug is prescribed in tablet form, but if it is not possible, or it is an emergency condition, the drug is administered intravenously by jetting, time of Lasix infusion should not be less than 1.5-2 minutes.

For mild-to-moderate edema, the initial dose of Lasix is 20-80 mg orally, or 20-40 mg intramuscularly or intravenously; if this is not successful, the dose can be increased by 40 mg when given orally, and by 20 mg when administered as an injection. The dose can be increased no earlier than 6-8 hours after the initial oral dose and no earlier than 2 hours after parenteral administration.

Dose adjustment occurs until adequate diuresis has occurred. A single dose adjusted in this way may be administered once or twice daily. The maximum effect of Lasix is observed if the drug is prescribed 2-4 times a week.

Key benefits

Key benefits include:

• Step 1: Consult a physician. Before you begin using Lasix, you should consult with your physician. Your doctor will examine you and determine if you have an indication for the use of this drug and prescribe the necessary dosage;
• Step 2: Take the medication. Lasix can be taken both orally and intravenously. Orally, the drug is taken with or without food, usually once or twice a day. If the drug is prescribed intravenously, it is injected by a healthcare provider;
• Step 3: Follow the doctor's recommendations. It is important to follow the doctor's recommendations for dosage and administration regimen. It is not recommended to change the dosage or stop taking it without consulting the doctor;
• Step 4: Monitor your condition. While taking Lasix, it is important to monitor your health and monitor your blood pressure and fluid levels. If any side effects occur, you should contact your doctor immediately;
• Step 5: Follow diet and restrictions. Lasix can cause loss of potassium, so it is important to monitor your levels of this element in your body and follow the dietary restrictions recommended by your doctor;
• Step 6: Discontinuing the drug. Discontinuing Lasix should be done on your doctor's recommendation. It is not recommended to stop taking Lasix on your own, even if your symptoms have improved, as this may have the opposite effect and worsen your condition.